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Free Biology Book> Biochemistry> Nucleic Acids

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Biochemistry

Introduction to Biochemistry

Water and Mineral Salts

Carbohydrates

Lipids

Proteins

Enzymes 

Nucleic Acids

 

 

Cell Biology 

Cell Organization

Membranes

Cytoskeleton and Cell Movement

Cellular Digestion and Secretion

Cell Nucleus

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Photosynthesis

Cellular Respiration

Protein Synthesis

 

 

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Reproduction

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View chapter-related images

nucleotide structure nitrogen-containing bases pyrimidine bases purine bases 

Watson and Crick DNA double helix DNA base pairing DNA replication RNA molecule 

RNA transcription reverse transcription

What are nucleic acids? What is the historic origin of this name?

 

Nucleic acids, DNA and RNA, are the molecules responsible for the hereditary information that commands the protein synthesis in the living beings. The name “nucleic” derives from the fact that they were discovered (by the Swiss biochemist Friedrich Miescher, in 1869) within the cell nucleus. In that time it was not known that those substances contained the hereditary information.

Of what units are nucleic acids constituted? What are the chemical entities that compose that unit?

 

Nucleic acids are formed by sequences of nucleotides.

 

Nucleotides are constituted by one molecule of sugar (ribose in DNA and deoxyribose in RNA) bound to one molecule of phosphate and to one nitrogen-containing base (adenine, uracil, cytosine or guanine, in RNA, and adenine, thymine, cytosine and guanine, in DNA).

What are pentoses? To what organic group do pentoses belong? Are nucleotides formed of only one type of pentose?

 

Pentoses are carbohydrates made of five carbons. Deoxyribose is the pentose that constitutes DNA nucleotides and ribose is the pentose that is part of RNA nucleotides.

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